Gang Chen, Ph.D.

Education
Ph.D. in cancer biology, Wayne State University, Detroit, Mich.

Graduate program in biochemistry, CalPoly State University, Pomona, Calif.

Bachelor of Science in chemistry, Jilin University, Changchun, China

Additional Training
Postdoctorate, Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, Wash.

Publications since 2010
Kristine C. Olson, Gang Chen and Christopher J. Lynch. Quantification of Branched-Chain Ketoacids in Tissue by Ultra Fast Liquid Chromatography-Mass Spectrometry. Analytical Biochemistry, 2013 May 14

Guodong Liu, Gang Chen, Lawrence I. Sinoway and Arthur Berg. Assessing the Impact of the NIH CTSA Program on Institutionally Sponsored Clinical Trials,CTS, 2013

Chen G, Giambrone NE, Lazarus P. Glucuronidation of trans-3'-hydroxycotinine by UGT2B17 and UGT2B10. Pharmacogenet Genomics. 2012 Mar;22(3):183-90. PMID: 22228205

Olson KC, Sun D, Chen G, Sharma AK, Amin S, Ropson IJ, Spratt TE, Lazarus P. Characterization of dibenzo[a,l]pyrene-trans-11,12-diol (dibenzo[def,p]chrysene) glucuronidation by UDP-glucuronosyltransferases. Chem Res Toxicol. 2011 Sep 19;24(9):1549-59. PMID: 21780761

Bushey RT, Chen G, Blevins-Primeau AS, Krzeminski J, Amin S, Lazarus P. Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis. Pharmacogenet Genomics. 2011 Feb;21(2):55-65. PMID: 21164388

Wilson RT, Roff AN, Dai PJ, Fortugno T, Douds J, Chen G, Grove GL, Nikiforova SO, Barnholtz-Sloan J, Frudakis T, Chinchilli VM, Hartman TJ, Demers LM, Shriver MD, Canfield VA, Cheng KC. Genetic Ancestry, Skin Reflectance and Pigmentation Genotypes in Association with Serum Vitamin D Metabolite Balance. Horm Mol Biol Clin Investig. 2011 Sep;7(1):279-293.

Sun D, Chen G, Dellinger RW, Sharma AK, Lazarus P. Characterization of 17-dihydroexemestane glucuronidation: potential role of the UGT2B17 deletion in exemestane pharmacogenetics. Pharmacogenet Genomics 2010; 20: 575-85.

Li Y, Ma C, Wang Z, et al. A disequilibrium model for detecting genetic mutations for cancer. J Theor Biol 2010; 265: 218-24.

Li Y, Berg A, Wu LR, Wang Z, Chen G, Wu R. Modeling the aneuploidy control of cancer. BMC Cancer 2010; 10: 346.

Gallagher CJ, Balliet RM, Sun D, Chen G, Lazarus P. Sex differences in UGT2B17 expression and activity. Drug Metab Dispos 2010.

Desai D, Kaushal N, Gandhi UH, et al. Synthesis and evaluation of the anti-inflammatory properties of selenium-derivatives of celecoxib. Chem Biol Interact 2010.

Chen G, Giambrone NE, Jr., Dluzen DF, et al. Glucuronidation Genotypes and Nicotine Metabolic Phenotypes: Importance of Functional UGT2B10 and UGT2B17 Polymorphisms. Cancer Res 2010; 70: 7543-52.

Chang JL, Chen G, Ulrich CM, et al. DNA damage and repair: fruit and vegetable effects in a feeding trial. Nutr Cancer 2010; 62: 329-35.

Bushey RT, Chen G, Blevins-Primeau AS, Krzeminski J, Amin S, Lazarus P. Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis. Pharmacogenetics and Genomics 2010; Publish Ahead of Print: 10.1097/FPC.0b013e328341db05.

Balliet RM, Chen G, Dellinger RW, Lazarus P. UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility. Drug Metab Dispos 2010; 38: 484-90.

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Dr. Gang Chen

Associate Research Professor
Pharmaceutical Sciences

gang8.chen@wsu.edu
509-368-6576

Office: PBS 427
P.O. Box 1495
Washington State University
Spokane, WA 99210-1495